`search_reactions`

Pack: rhea · Endpoint: https://gateway.pipeworx.io/rhea/mcp

Search Rhea, the expert-curated database of biochemical reactions (the reaction reference used by UniProt and KEGG). Find enzyme/metabolic reactions by compound name, ChEBI id, EC number, or keyword and get the balanced plain-text reaction equation plus EC and ChEBI cross-references. Keyless.

Parameters

Name	Type	Required	Description
`query`	string	yes	Compound name, ChEBI id, EC number (e.g. “1.1.1.1”), UniProt accession, or free-text keyword.
`limit`	number	no	Max reactions to return (default 15, max 100).

Example call

Arguments

{
  "query": "glucose"
}

curl

curl -X POST https://gateway.pipeworx.io/rhea/mcp \
  -H 'Content-Type: application/json' \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"search_reactions","arguments":{"query":"glucose"}}}'

TypeScript (@pipeworx/sdk)

import { Pipeworx } from '@pipeworx/sdk';
const pipeworx = new Pipeworx();

const result = await pipeworx.call('search_reactions', {
  "query": "glucose"
});

More examples

{
  "query": "1.1.1.1",
  "limit": 10
}

Connect

Add this to your MCP client config, or use one-click install buttons:

{
  "mcpServers": {
    "rhea": {
      "url": "https://gateway.pipeworx.io/rhea/mcp"
    }
  }
}

See Getting Started for client-specific install steps.

search_reactions