Rhea (Reactions)

live Data

Rhea MCP — expert-curated database of biochemical reactions.

2 tools
0ms auth
free tier 50 calls/day

Tools

search_reactions

Search Rhea, the expert-curated database of biochemical reactions (the reaction reference used by UniProt and KEGG). Find enzyme/metabolic reactions by compound name, ChEBI id, EC number, or keyword a

No parameters required.

▶ Try it
get_reaction

Fetch a single Rhea reaction by its Rhea id (e.g. "RHEA:14293" or "14293"). Returns the balanced plain-text equation plus EC number, ChEBI compound, UniProt enzyme and PubMed cross-references. Rhea is

No parameters required.

▶ Try it

Test with curl

The gateway speaks JSON-RPC 2.0 over HTTP POST. You can test any pack directly from the terminal.

List available tools
bash 
curl -X POST https://gateway.pipeworx.io/rhea/mcp \
  -H "Content-Type: application/json" \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/list"}'
Call a tool
bash 
curl -X POST https://gateway.pipeworx.io/rhea/mcp \
  -H "Content-Type: application/json" \
  -d '{"jsonrpc":"2.0","id":2,"method":"tools/call","params":{"name":"search_reactions","arguments":{}}}'

Use with the SDK

Install @pipeworx/sdk to call tools from any TypeScript/Node project.

TypeScript 
import { Pipeworx } from '@pipeworx/sdk';
const px = new Pipeworx();
const result = await px.call("search_reactions", {});
ask_pipeworx 
// Or ask in plain English:
const answer = await px.ask("rhea mcp — expert-curated database of biochemical reactions");