`target`

Pack: opentargets · Endpoint: https://gateway.pipeworx.io/opentargets/mcp

“Drug target profile for [gene]” / “is [gene] a druggable target” / “[gene] target info” / “target ID [ENSG…]” — fetch a drug-target profile (Open Targets uses Ensembl gene IDs as target identifiers). Returns approved symbol, name, biotype, protein IDs, pathways, synonyms. Use for target characterization in drug discovery.

Parameters

Name	Type	Required	Description
`ensembl_id`	string	yes	e.g. “ENSG00000141510” (TP53)

Example call

Arguments

{
  "ensembl_id": "ENSG00000141510"
}

curl

curl -X POST https://gateway.pipeworx.io/opentargets/mcp \
  -H 'Content-Type: application/json' \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"target","arguments":{"ensembl_id":"ENSG00000141510"}}}'

TypeScript (@pipeworx/sdk)

import { Pipeworx } from '@pipeworx/sdk';
const pipeworx = new Pipeworx();

const result = await pipeworx.call('target', {
  "ensembl_id": "ENSG00000141510"
});

More examples

{
  "ensembl_id": "ENSG00000169245"
}

Response shape

Field	Type	Description
`data`	object

Full JSON Schema

{
  "type": "object",
  "properties": {
    "data": {
      "type": "object",
      "properties": {
        "target": {
          "type": "object",
          "properties": {
            "id": {
              "type": "string",
              "description": "Ensembl target ID"
            },
            "approvedSymbol": {
              "type": "string",
              "description": "Approved gene symbol"
            },
            "approvedName": {
              "type": "string",
              "description": "Approved gene name"
            },
            "biotype": {
              "type": "string",
              "description": "Gene biotype"
            },
            "proteinIds": {
              "type": "array",
              "items": {
                "type": "object",
                "properties": {
                  "id": {
                    "type": "string",
                    "description": "Protein ID"
                  },
                  "source": {
                    "type": "string",
                    "description": "ID source"
                  }
                }
              }
            },
            "pathways": {
              "type": "array",
              "items": {
                "type": "object",
                "properties": {
                  "pathwayId": {
                    "type": "string",
                    "description": "Pathway ID"
                  },
                  "pathway": {
                    "type": "string",
                    "description": "Pathway name"
                  }
                }
              }
            },
            "synonyms": {
              "type": "array",
              "items": {
                "type": "object",
                "properties": {
                  "label": {
                    "type": "string",
                    "description": "Synonym label"
                  },
                  "source": {
                    "type": "string",
                    "description": "Synonym source"
                  }
                }
              }
            }
          }
        }
      }
    }
  }
}

Connect

Add this to your MCP client config, or use one-click install buttons:

{
  "mcpServers": {
    "opentargets": {
      "url": "https://gateway.pipeworx.io/opentargets/mcp"
    }
  }
}

See Getting Started for client-specific install steps.

target