Open Targets
live BioDrug DiscoveryOpen Targets disease/target/drug knowledge graph (GraphQL). Keyless.
7 tools
0ms auth
free tier 50 calls/day
Tools
target
required: ensembl_id Target profile by Ensembl id.
Parameters
Name Type Description
ensembl_id req string — Try it
Response
disease
required: efo_id Disease profile by EFO id.
Parameters
Name Type Description
efo_id req string — Try it
Response
drug
required: chembl_id Drug profile by ChEMBL id.
Parameters
Name Type Description
chembl_id req string — Try it
Response
search
required: query Platform search.
Parameters
Name Type Description
query req string — entity opt string — size opt number — Try it
Response
target_associations
required: ensembl_id Top diseases for a target.
Parameters
Name Type Description
ensembl_id req string — size opt number — Try it
Response
disease_associations
required: efo_id Top targets for a disease.
Parameters
Name Type Description
efo_id req string — size opt number — Try it
Response
target_known_drugs
required: ensembl_id Clinically tested drugs for a target.
Parameters
Name Type Description
ensembl_id req string — size opt number — Try it
Response
Test with curl
The gateway speaks JSON-RPC 2.0 over HTTP POST. You can test any pack directly from the terminal.
List available tools
bash
curl -X POST https://gateway.pipeworx.io/opentargets/mcp \
-H "Content-Type: application/json" \
-d '{"jsonrpc":"2.0","id":1,"method":"tools/list"}'Call a tool
bash
curl -X POST https://gateway.pipeworx.io/opentargets/mcp \
-H "Content-Type: application/json" \
-d '{"jsonrpc":"2.0","id":2,"method":"tools/call","params":{"name":"target","arguments":{"ensembl_id": "example"}}}'Use with the SDK
Install @pipeworx/sdk to call tools from any TypeScript/Node project.
TypeScript
import { Pipeworx } from '@pipeworx/sdk';
const px = new Pipeworx();
const result = await px.call("target", {"ensembl_id":"example"}); ask_pipeworx
// Or ask in plain English:
const answer = await px.ask("open targets disease/target/drug knowledge graph (graphql)");Related packs
Other Pipeworx packs in the same categories (Bio, Drug Discovery):