Live ClinicalTrials.gov, FDA, PubMed and Medicare — read straight from the source.

Clinical answers, cited.
281 PharmaPulse tools behind one URL.
Frontier models: 100% correct with Pipeworx, 63% with web search

Ask what phase a trial is in, whether the FDA has flagged a safety signal, what a drug's label warns about, or whether Medicare will pay for it — and get the answer with the record it came from. Your agent reads the primary sources directly, so nothing depends on what it happened to memorise during training.

One connection · no per-source API keys · free to start

← All verticals

Included Packs

🧬
ClinicalTrials.gov

Search 400K+ clinical trials. Filter by phase, status, sponsor, condition. Track pipeline progress.

💊
OpenFDA

Drug adverse events (FAERS), FDA approvals, drug labels, recalls, safety signal detection.

💉
RxNorm

Drug name normalization (brand ↔ generic), drug interactions, NDC codes.

📄
SEC EDGAR

Pharma company financials, 10-K/10-Q filings, R&D spend, revenue, patent cliff disclosures.

📚
PubMed

Search 40M+ biomedical citations and research publications.

📋
Patents

Search patent filings for drug compounds, methods, formulations.

🧬
Genomics & Variants

BioThings (MyGene / MyVariant / MyDisease / MyChem), GWAS Catalog, Ensembl, gnomAD — gene, variant, and disease annotation.

🎗️
Cancer Genomics

NCI GDC and cBioPortal — cancer studies, cases, mutations, and genomic files across TCGA/TARGET/CPTAC.

🔬
Proteins & Structure

UniProt, AlphaFold, RCSB PDB, Human Protein Atlas, InterPro — sequences, 3D structures, expression, and domains.

🔁
Pathways & Reactions

KEGG, Reactome, WikiPathways, Rhea, QuickGO — metabolic/signaling pathways, biochemical reactions, and Gene Ontology.

🔗
Interactions & Targets

IntAct, STRING, Guide to PHARMACOLOGY — protein interactions and quantitative drug-target pharmacology.

⚗️
Chemistry

PubChem, ChEMBL, NCI CACTUS — compound properties, bioactivity, and chemical identifier resolution.

📊
Omics Datasets

Expression Atlas (transcriptomics), PRIDE (proteomics), MetaboLights (metabolomics) — the EBI omics trio.

🧫
Model Organisms & Literature

SGD (yeast), PomBase (fission yeast), Europe PMC, DailyMed, MedlinePlus — curated genetics and biomedical references.

Setup

1
Sign up for Pipeworx

Create a free account at /signup and grab your API key from /account.

2
Connect to Claude

Choose one of these options:

Option A — Claude on the web

Open claude.ai/customize/connectors, click Add custom connector, name it Pipeworx Pharma and paste this URL. Leave the OAuth client ID and secret blank — the connector registers itself.

connector URL
https://gateway.pipeworx.io/mcp?vertical=pharma

Then click Connect and sign in with GitHub. That step is free and takes you from 50 calls a day to 200 — same connection either way, and you can skip it and sign in later. In a new chat, open the tools menu and enable the connector.

Custom connectors need a paid Claude plan — that is an Anthropic gate, not a Pipeworx one.

Option B — Persistent MCP config

Add this to your claude_desktop_config.json:

claude_desktop_config.json
{
  "mcpServers": {
    "pipeworx-pharma": {
      "command": "npx",
      "args": [
        "-y",
        "mcp-remote",
        "https://gateway.pipeworx.io/mcp?vertical=pharma",
        "--header",
        "Authorization:Bearer YOUR_API_KEY"
      ]
    }
  }
}
Option C — Session only

Paste this into Claude to use for one conversation:

prompt
Use this MCP server for this conversation:

npx -y mcp-remote "https://gateway.pipeworx.io/mcp?vertical=pharma" --header "Authorization:Bearer YOUR_API_KEY"

Then search ClinicalTrials.gov for Phase 3 oncology trials.
3
No API keys needed

All data sources are free public APIs. Just sign up and start querying.

Tools

The clinical & competitive-intelligence core is listed below. This vertical also bundles the full research-bioinformatics layer — genomics, proteomics, protein structure, pathways, interactions, and chemistry (BioThings, KEGG, Reactome, UniProt, AlphaFold, ChEMBL, Guide to PHARMACOLOGY, Expression Atlas / PRIDE / MetaboLights, and more). Connect with ?vertical=pharma to get them all, or browse the full pack catalog.

ClinicalTrials.gov 5 tools

ct_search Search clinical trials by keyword, condition, or intervention
ct_get_study Get detailed study record by NCT ID
ct_count_by_condition Count trials by condition and phase
ct_sponsor_trials List trials for a specific sponsor
ct_recent_updates Recently updated or posted trials

OpenFDA 5 tools

fda_drug_events Search adverse event reports (FAERS)
fda_drug_approvals FDA drug approval history
fda_drug_labels Drug labeling and package insert data
fda_drug_recalls Drug recall enforcement reports
fda_event_counts Aggregate adverse event counts by drug or reaction

RxNorm 5 tools

rxnorm_search Search drugs by name (brand or generic)
rxnorm_get_properties Get drug properties and attributes
rxnorm_related Find related drugs (brand/generic mappings)
rxnorm_interactions Check drug-drug interactions
rxnorm_ndc Look up National Drug Code identifiers

SEC EDGAR 5 tools

edgar_search_filings Full-text search across all SEC filings
edgar_company_filings List filings for a specific company
edgar_company_facts All XBRL facts for a company
edgar_company_concept Single XBRL concept time series
edgar_ticker_to_cik Convert ticker symbol to CIK number

PubMed 1 tool

search_pubmed Search biomedical literature and citations

Patents 2 tools

search_patents Search patent filings by keyword or assignee
get_patent Get full patent details by number

FRED 2 tools

fred_get_series Fetch time series observations
fred_search Search for economic data series

Common questions

What data sources are included in PharmaPulse?

ClinicalTrials.gov (active and completed trials by phase, sponsor, condition), OpenFDA (adverse events, drug approvals, label data), RxNorm (drug normalization, ingredient mapping), DailyMed (structured labels), SEC EDGAR (pharma company filings), and USPTO (patents and trademarks). Covers competitive intelligence, safety analysis, and clinical pipeline tracking.

Can I get a complete safety profile for a drug from one call?

Yes — the drug_safety_profile prompt and the pharma_drug_profile _intel tool fan out across RxNorm, OpenFDA adverse events, ClinicalTrials, and DailyMed in parallel. A query like "What are the side effects of Ozempic?" returns adverse event counts (54k+ reports for semaglutide), interaction warnings, and label sections in one round trip.

How do I track Phase 3 trials or competitive pipelines for a condition?

ClinicalTrials.gov tools let an agent filter trials by phase, status (recruiting, active, completed), condition, sponsor, and intervention type. Combine with EDGAR filings on the sponsor companies and USPTO patent search on the molecule for a full competitive-intelligence brief.

Is the drug data live or cached?

ClinicalTrials.gov updates are typically reflected within hours. OpenFDA adverse events are refreshed quarterly by FDA, with the most recent quarter usually 2–3 months behind. RxNorm releases monthly. Every response includes _meta.cache.fresh_until so agents can decide whether to refetch.