`search`

Pack: uniprot · Endpoint: https://gateway.pipeworx.io/uniprot/mcp

“Find protein [name]” / “look up [gene] in UniProt” / “BRCA1 / TP53 / insulin protein info” / “all proteins for [organism]” — UniProtKB search via Lucene-style queries (e.g. “gene:BRCA1 AND organism_id:9606” for human BRCA1). UniProt is the authoritative protein-sequence-and-function database — use for protein characterization, function annotation, sequence retrieval, and cross-references to PDB/GO/PubMed.

Parameters

Name	Type	Required	Description
`query`	string	yes
`format`	string	no	json (default) \| tsv \| fasta \| xml
`size`	number	no	1-500 (default 25)
`fields`	string	no	Comma-sep returned fields (json/tsv only).

Example call

Arguments

{
  "query": "gene:BRCA1 AND organism_id:9606"
}

curl

curl -X POST https://gateway.pipeworx.io/uniprot/mcp \
  -H 'Content-Type: application/json' \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"search","arguments":{"query":"gene:BRCA1 AND organism_id:9606"}}}'

TypeScript (@pipeworx/sdk)

import { Pipeworx } from '@pipeworx/sdk';
const pipeworx = new Pipeworx();

const result = await pipeworx.call('search', {
  "query": "gene:BRCA1 AND organism_id:9606"
});

More examples

{
  "query": "protein_name:hemoglobin AND organism_id:9606",
  "format": "fasta",
  "size": 50
}

Response shape

Field	Type	Description
`results`	array	Array of search result entries
`facets`	array	Search facets for filtering

Full JSON Schema

{
  "type": "object",
  "description": "UniProtKB search results",
  "properties": {
    "results": {
      "type": "array",
      "description": "Array of search result entries",
      "items": {
        "type": "object",
        "description": "Protein entry result"
      }
    },
    "facets": {
      "type": "array",
      "description": "Search facets for filtering"
    }
  }
}

Connect

Add this to your MCP client config, or use one-click install buttons:

{
  "mcpServers": {
    "uniprot": {
      "url": "https://gateway.pipeworx.io/uniprot/mcp"
    }
  }
}

See Getting Started for client-specific install steps.

search