@pipeworx/uniprot

Connect: https://gateway.pipeworx.io/uniprot/mcp · Install: one-click buttons

Tools: 6

UniProt MCP — the canonical protein-sequence and -function knowledge-base from EBI. Keyless.

Tools

• search(query, format?, size?) — UniProtKB search (Lucene-style query)
• get(accession, format?) — single entry by accession (e.g. P12345)
• proteomes_search(query, size?) — search proteomes
• taxonomy_search(query, size?) — search NCBI taxonomy as exposed by UniProt
• keyword(keyword_id) — UniProt keyword info
• feature_summary(accession) — summary of feature annotations (domain, mutagen, etc)

Data source

https://rest.uniprot.org/ — public, no API key.

Tools

• search — “Find protein [name]” / “look up [gene] in UniProt” / “BRCA1 / TP53 / insulin protein info” / “all proteins for [organism]” — UniProtKB search via Lucene-style queries (e.g. “gene:BRCA1 AND organism_i
• get — “Fetch protein [P12345]” / “UniProt entry for [accession]” / “FASTA sequence for [protein]” — single UniProtKB entry by accession (e.g. P12345 or P38398 for BRCA1_HUMAN). Returns full protein record:
• proteomes_search — “Reference proteome for [organism]” / “complete protein set of [species]” — search UniProt reference proteomes (the curated representative protein set per organism). Use as a starting point for genome
• taxonomy_search — “NCBI taxonomy ID for [organism]” / “taxid for [species]” / “look up [Latin name] in NCBI taxonomy” — search NCBI Taxonomy via UniProt’s mirror. Returns taxonomic IDs you can use as organism_id filter
• keyword — “UniProt keyword KW-N info” / “what does keyword [X] mean” — fetch a UniProt controlled-vocabulary keyword by ID. Use to look up annotation tags like “Kinase” / “Membrane” / “Disease-associated”.
• feature_summary — “Domain map of [protein]” / “annotated features of [accession]” / “what regions / sites does [protein] have” — annotated features (domains, active sites, transmembrane regions, mutagenesis sites, glyc