`variation_spdi_to_rsids`

Pack: ncbi-variation · Endpoint: https://gateway.pipeworx.io/ncbi-variation/mcp

No MCP client? Call it directly: GET https://gateway.pipeworx.io/v1/tools/variation_spdi_to_rsids for the schema, then POST the same URL with its arguments for the data.

Maps a SPDI genomic coordinate and alleles back to the dbSNP rsIDs, via NCBI Variation Services.

Tool description as the model sees it

Look up the dbSNP rsIDs that a SPDI allele maps to, via NCBI Variation Services. AUTHORITATIVE for the reverse direction — you have a genomic coordinate and alleles from a VCF or a pipeline and need the rsID other databases key on. SPDI is 0-BASED, unlike HGVS: “NC_000007.14:140753335:A:T” is the same variant as “NC_000007.14:g.140753336A>T”.

Parameters

Name	Type	Required	Description
`spdi`	string	yes	SPDI as seq_id:position:deleted:inserted, 0-based position. e.g. “NC_000007.14:140753335:A:T”.

Example call

Arguments

{
  "spdi": "NC_000007.14:140753335:A:T"
}

curl

curl -X POST https://gateway.pipeworx.io/ncbi-variation/mcp \
  -H 'Content-Type: application/json' \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"variation_spdi_to_rsids","arguments":{"spdi":"NC_000007.14:140753335:A:T"}}}'

TypeScript (@pipeworx/sdk)

import { Pipeworx } from '@pipeworx/sdk';
const pipeworx = new Pipeworx();

const result = await pipeworx.call('variation_spdi_to_rsids', {
  "spdi": "NC_000007.14:140753335:A:T"
});

Connect

Add this to your MCP client config, or use one-click install buttons:

{
  "mcpServers": {
    "ncbi-variation": {
      "url": "https://gateway.pipeworx.io/ncbi-variation/mcp"
    }
  }
}

See Getting Started for client-specific install steps.

variation_spdi_to_rsids