variant
Pack: myvariant · Endpoint: https://gateway.pipeworx.io/myvariant/mcp
Get the full merged annotation for a single human genetic variant by its HGVS id (e.g. “chr7:g.140453136A>T”). Returns annotations aggregated from dbSNP, ClinVar (pathogenicity / clinical significance), CADD and dbNSFP (deleteriousness/conservation scores), and gnomAD (population allele frequencies). Use to look up a known variant and read its pathogenicity and population frequency.
Parameters
| Name | Type | Required | Description |
|---|---|---|---|
id | string | yes | An HGVS variant id, e.g. “chr7:g.140453136A>T”. |
fields | string | no | Comma-separated return fields (default: all). e.g. “clinvar,gnomad_genome.af,cadd.phred”. |
Example call
curl -X POST https://gateway.pipeworx.io/myvariant/mcp \
-H 'Content-Type: application/json' \
-d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"variant","arguments":{}}}'Connect
Add this to your MCP client config, or use one-click install buttons:
{
"mcpServers": {
"myvariant": {
"url": "https://gateway.pipeworx.io/myvariant/mcp"
}
}
}See Getting Started for client-specific install steps.