@pipeworx/mhra-uk

Connect: https://gateway.pipeworx.io/mhra-uk/mcp · Install: one-click buttons

Tools: 4

UK medicines register — the MHRA products database behind products.mhra.gov.uk. Post-Brexit the EMA register no longer covers the UK, so this is the UK authorisation surface.

What this register actually is

It is an index of documents — Summaries of Product Characteristics, patient information leaflets and public assessment reports, as PDFs — with metadata about each. It is not a register of structured product records. There is no indication field, no pathway field and no authorisation-status field in it.

That shapes every tool here. mhra_product returns the document metadata and the authoritative PDF URL rather than a summary of the document, because the authorised indication text is written in section 4.1 of the SmPC and nowhere else. authorisation_status is always unknown, with a note saying why: the only status-shaped field is release_state, which is Y on all 79,112 released documents and means “published”, not “currently authorised”. Reporting it as authorisation status would be a guess wearing a field name.

Tools

• mhra_search(query, doc_type?, territory?, limit?, offset?) — by product, brand or active substance. One row per document.
• mhra_product(pl_number) — every document for one licence, grouped by type. Accepts PL 29831/0798, PL29831/0798, PL298310798 and the PLGB / PLNI forms.
• mhra_recent_changes(since, doc_type?, limit?) — documents added or revised since a date, newest first. Idempotent on replay.
• mhra_snapshot() — total count, counts per document type, newest document date, and the paging recipe. Counts, never documents.

Licence prefixes are not spellings of each other

PL is UK-wide, PLGB is Great Britain only, PLNI is Northern Ireland only. Measured 2026-09-07: UK 64,126 documents, GB 8,428, NI 48. Treating them as interchangeable answers “is this authorised in the UK?” with a licence that may cover a small fraction of it.

Enumeration

There is no bulk download. Walk the register with mhra_search({query: "*", limit: 50, offset: N}), stepping offset by 50. mhra_snapshot() returns the current total so you know when to stop.

recent_changes reports new and changed, NOT withdrawn

The register records documents, and a withdrawal is not published as an event. covers on every response says so. Do not read an absence as a withdrawal.

Fragility worth knowing

Search runs on Azure Cognitive Search using MHRA’s own client key — the one shipped to every browser that loads products.mhra.gov.uk. No account, payment or agreement stands between anyone and this data. But if MHRA rotates that key this pack stops working, and the fix is to read the current one out of their public bundle again. medicines.api.mhra.gov.uk/graphql also appears in their bundle and 503s on every request; do not build on it.

created is sortable but not filterable on this index, which is why recent_changes orders newest-first and stops at the cutoff rather than pushing a date filter upstream.

Tools

• mhra_search — Search the UK MHRA products register by product name, brand name or active substance — e.g. “ibuprofen”, “Nurofen”, “atorvastatin”. Post-Brexit the EMA register does not cover the UK, so this is the U
• mhra_product — Every MHRA document held for one UK licence number, grouped by document type — the SmPC that carries the authorised indications, the patient leaflet, and the public assessment report where one exists.
• mhra_recent_changes — MHRA documents added or revised since a date, newest first — the weekly-refresh feed. Pass an ISO date such as “2026-09-01”. Returns the same rows as mhra_search plus the cutoff that was applied, so r
• mhra_snapshot — How big the UK register currently is and how to walk all of it: total document count, the count per document type, the newest document date, and the paging recipe for a full enumeration. MHRA publishe