`isrctn_search`

Pack: isrctn · Connect: https://pipeworx.io/mcp (see Connect below for a single-pack URL)

No MCP client? Call it directly: GET https://gateway.pipeworx.io/v1/tools/isrctn_search for the schema, then POST the same URL with its arguments for the data.

Search the ISRCTN registry (isrctn.com) — the UK-based international clinical trial registry — by free text and/or by condition/intervention. Use for “studies on and <drug/intervention>”, “trials of psilocybin for depression”, or any UK/international trial not necessarily registered on ClinicalTrials.gov. At least one of query/condition/intervention is required. Combining condition and intervention narrows to trials registered under BOTH (an AND, not an OR) — a real zero means no ISRCTN trial currently pairs that condition with that intervention, and the tool says so explicitly rather than guessing. status filters on a DERIVED recruitment status (ISRCTN’s feed carries no status field) computed from each trial’s recruitment dates — see status_basis on every returned trial.

Parameters

Name	Type	Required	Description
`query`	string	no	Free-text search terms (title, summary, eligibility criteria, etc.) — e.g. “psilocybin” or “psilocybin depression” (multiple words are ANDed, not ORed). Optional if condition and/or intervention are given.
`condition`	string	no	Filter to trials whose registered CONDITION field matches this phrase (e.g. “stroke”, “treatment-resistant depression”).
`intervention`	string	no	Filter to trials whose registered INTERVENTION field matches this phrase (e.g. “psilocybin”, “COMP360”).
`status`	string	no	Filter on the DERIVED recruitment status (case-insensitive substring match) — e.g. “recruiting”, “completed”, “not yet recruiting”. Applied client-side over the fetched batch (see `status_filter_scanned` in the response), since ISRCTN’s feed has no status field to filter on server-side.
`limit`	number	no	Max trials to return (1-${MAX_LIMIT}, default ${DEFAULT_LIMIT}).

Example call

Arguments

{
  "query": "psilocybin depression",
  "limit": 5
}

curl

curl -X POST https://gateway.pipeworx.io/isrctn/mcp \
  -H 'Content-Type: application/json' \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"isrctn_search","arguments":{"query":"psilocybin depression","limit":5}}}'

TypeScript (@pipeworx/sdk)

import { Pipeworx } from '@pipeworx/sdk';
const pipeworx = new Pipeworx();

const result = await pipeworx.call('isrctn_search', {
  "query": "psilocybin depression",
  "limit": 5
});

Connect

Add this to your MCP client config — every tool in the catalog, including this one — or use one-click install buttons:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://pipeworx.io/mcp"
    }
  }
}

Connect to just the isrctn pack

{
  "mcpServers": {
    "isrctn": {
      "url": "https://gateway.pipeworx.io/isrctn/mcp"
    }
  }
}

See Getting Started for client-specific install steps.

isrctn_search