xrefs

Pack: ensembl · Endpoint: https://gateway.pipeworx.io/ensembl/mcp

“What’s the UniProt / HGNC / RefSeq ID for [gene]” / “cross-references for [gene symbol]” — external database IDs (UniProt, RefSeq, HGNC, Entrez, OMIM, etc.) for a gene symbol. Use to map between bio-database identifier spaces.

Parameters

NameTypeRequiredDescription
speciesstringyes
symbolstringyes

Example call

Arguments

{
  "species": "human",
  "symbol": "TP53"
}

curl

curl -X POST https://gateway.pipeworx.io/ensembl/mcp \
  -H 'Content-Type: application/json' \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"xrefs","arguments":{"species":"human","symbol":"TP53"}}}'

TypeScript (@pipeworx/sdk)

import { Pipeworx } from '@pipeworx/sdk';
const pipeworx = new Pipeworx();

const result = await pipeworx.call('xrefs', {
  "species": "human",
  "symbol": "TP53"
});

Response shape

Always returns: items, count

FieldTypeDescription
itemsarrayExternal cross-references for a gene symbol
countintegerNumber of items returned.
Full JSON Schema
{
  "type": "object",
  "properties": {
    "items": {
      "type": "array",
      "description": "External cross-references for a gene symbol",
      "items": {
        "type": "object",
        "properties": {
          "dbname": {
            "type": "string",
            "description": "Database name (UniProtKB, NCBI, etc)"
          },
          "display_id": {
            "type": "string",
            "description": "External identifier"
          },
          "primary_id": {
            "type": "string",
            "description": "Primary external ID"
          },
          "xref_id": {
            "type": "integer",
            "description": "Xref database ID"
          },
          "description": {
            "type": "string",
            "description": "Cross-reference description"
          }
        }
      }
    },
    "count": {
      "type": "integer",
      "description": "Number of items returned."
    }
  },
  "required": [
    "items",
    "count"
  ]
}

Connect

Add this to your MCP client config, or use one-click install buttons:

{
  "mcpServers": {
    "ensembl": {
      "url": "https://gateway.pipeworx.io/ensembl/mcp"
    }
  }
}

See Getting Started for client-specific install steps.

Regenerated from source · build July 6, 2026