`activities`

Pack: chembl · Endpoint: https://gateway.pipeworx.io/chembl/mcp

Retrieve bioactivity records from ChEMBL filtered by molecule_chembl_id and/or target_chembl_id; returns IC50/Ki/EC50 values, assay descriptions, and units.

Parameters

Name	Type	Required	Description
`molecule_chembl_id`	string	no
`target_chembl_id`	string	no
`limit`	number	no	1-1000 (default 25).

Example call

Arguments

{
  "molecule_chembl_id": "CHEMBL25"
}

curl

curl -X POST https://gateway.pipeworx.io/chembl/mcp \
  -H 'Content-Type: application/json' \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"activities","arguments":{"molecule_chembl_id":"CHEMBL25"}}}'

TypeScript (@pipeworx/sdk)

import { Pipeworx } from '@pipeworx/sdk';
const pipeworx = new Pipeworx();

const result = await pipeworx.call('activities', {
  "molecule_chembl_id": "CHEMBL25"
});

More examples

{
  "target_chembl_id": "CHEMBL614",
  "limit": 100
}

Response shape

Field	Type	Description
`activities`	array
`page_meta`	object

Full JSON Schema

{
  "type": "object",
  "properties": {
    "activities": {
      "type": "array",
      "items": {
        "type": "object",
        "properties": {
          "action_type": {
            "type": "null"
          },
          "activity_comment": {
            "type": [
              "null",
              "string"
            ]
          },
          "activity_id": {
            "type": "number"
          },
          "activity_properties": {
            "type": "array",
            "items": {}
          },
          "assay_chembl_id": {
            "type": "string"
          },
          "assay_description": {
            "type": "string"
          },
          "assay_type": {
            "type": "string"
          },
          "assay_variant_accession": {
            "type": "null"
          },
          "assay_variant_mutation": {
            "type": "null"
          },
          "bao_endpoint": {
            "type": "string"
          },
          "bao_format": {
            "type": "string"
          },
          "bao_label": {
            "type": "string"
          },
          "canonical_smiles": {
            "type": "string"
          },
          "data_validity_comment": {
            "type": "null"
          },
          "data_validity_description": {
            "type": "null"
          },
          "document_chembl_id": {
            "type": "string"
          },
          "document_journal": {
            "type": "string"
          },
          "document_year": {
            "type": "number"
          },
          "ligand_efficiency": {
            "type": [
              "null",
              "object"
            ]
          },
          "modality": {
            "type": "null"
          },
          "molecule_chembl_id": {
            "type": "string"
          },
          "molecule_pref_name": {
            "type": "null"
          },
          "parent_molecule_chembl_id": {
            "type": "string"
          },
          "pchembl_value": {
            "type": [
              "null",
              "string"
            ]
          },
          "potential_duplicate": {
            "type": "number"
          },
          "qudt_units": {
            "type": "string"
          },
          "record_id": {
            "type": "number"
          },
          "relation": {
            "type": [
              "string",
              "null"
            ]
          },
          "src_id": {
            "type": "number"
          },
          "standard_flag": {
            "type": "number"
          },
          "standard_relation": {
            "type": [
              "string",
              "null"
            ]
          },
          "standard_text_value": {
            "type": "null"
          },
          "standard_type": {
            "type": "string"
          },
          "standard_units": {
            "type": "string"
          },
          "standard_upper_value": {
            "type": "null"
          },
          "standard_value": {
            "type": [
              "string",
              "null"
            ]
          },
          "target_chembl_id": {
            "type": "string"
          },
          "target_organism": {
            "type": [
              "string",
              "null"
            ]
          },
          "target_pref_name": {
            "type": "string"
          },
          "target_tax_id": {
            "type": [
              "string",
              "null"
            ]
          },
          "text_value": {
            "type": "null"
          },
          "toid": {
            "type": "null"
          },
          "type": {
            "type": "string"
          },
          "units": {
            "type": "string"
          },
          "uo_units": {
            "type": "string"
          },
          "upper_value": {
            "type": "null"
          },
          "value": {
            "type": [
              "string",
              "null"
            ]
          }
        }
      }
    },
    "page_meta": {
      "type": "object",
      "properties": {
        "limit": {
          "type": "number"
        },
        "next": {
          "type": "string"
        },
        "offset": {
          "type": "number"
        },
        "previous": {
          "type": "null"
        },
        "total_count": {
          "type": "number"
        }
      }
    }
  },
  "description": "Activity records"
}

Connect

Add this to your MCP client config, or use one-click install buttons:

{
  "mcpServers": {
    "chembl": {
      "url": "https://gateway.pipeworx.io/chembl/mcp"
    }
  }
}

See Getting Started for client-specific install steps.

activities