`rxnorm_interactions`

Pack: rxnorm · Endpoint: https://gateway.pipeworx.io/rxnorm/mcp

Check drug-drug interactions by RxCUI. Returns interaction pairs and severity levels. Use to identify safety risks when combining medications.

Parameters

Name	Type	Required	Description
`rxcui`	string	yes	RxNorm concept ID of the drug to check interactions for
`sources`	string	no	Optional interaction source filter: “DrugBank”, “ONCHigh”, or omit for all sources

Example call

Arguments

{
  "rxcui": "7052"
}

curl

curl -X POST https://gateway.pipeworx.io/rxnorm/mcp \
  -H 'Content-Type: application/json' \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"name":"rxnorm_interactions","arguments":{"rxcui":"7052"}}}'

TypeScript (@pipeworx/sdk)

import { Pipeworx } from '@pipeworx/sdk';
const pipeworx = new Pipeworx();

const result = await pipeworx.call('rxnorm_interactions', {
  "rxcui": "7052"
});

More examples

{
  "rxcui": "161",
  "sources": "DrugBank"
}

Response shape

Always returns: rxcui, interactions

Field	Type	Description
`rxcui`	string	RxNorm concept unique identifier queried
`interactions`	array	Drug-drug interaction groups by source

Full JSON Schema

{
  "type": "object",
  "properties": {
    "rxcui": {
      "type": "string",
      "description": "RxNorm concept unique identifier queried"
    },
    "interactions": {
      "type": "array",
      "description": "Drug-drug interaction groups by source",
      "items": {
        "type": "object",
        "properties": {
          "source": {
            "type": "string",
            "description": "Interaction source name (e.g., DrugBank, ONCHigh)"
          },
          "disclaimer": {
            "type": "string",
            "description": "Source disclaimer or warning text"
          },
          "pairs": {
            "type": "array",
            "description": "Specific interaction pairs with severity",
            "items": {
              "type": "object",
              "properties": {
                "drugs": {
                  "type": "array",
                  "description": "Drugs involved in interaction",
                  "items": {
                    "type": "object",
                    "properties": {
                      "rxcui": {
                        "type": "string",
                        "description": "RxNorm concept ID"
                      },
                      "name": {
                        "type": "string",
                        "description": "Drug name"
                      }
                    },
                    "required": [
                      "rxcui",
                      "name"
                    ]
                  }
                },
                "severity": {
                  "type": "string",
                  "description": "Interaction severity level"
                },
                "description": {
                  "type": "string",
                  "description": "Interaction description and clinical significance"
                }
              },
              "required": [
                "drugs",
                "severity",
                "description"
              ]
            }
          }
        },
        "required": [
          "source",
          "disclaimer",
          "pairs"
        ]
      }
    }
  },
  "required": [
    "rxcui",
    "interactions"
  ]
}

Connect

Add this to your MCP client config, or use one-click install buttons:

{
  "mcpServers": {
    "rxnorm": {
      "url": "https://gateway.pipeworx.io/rxnorm/mcp"
    }
  }
}

See Getting Started for client-specific install steps.

rxnorm_interactions